D-Pantothenic acid( —— )

Catalog No. M15989 CAS No. 79-83-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

D-Pantothenic acid
Note

Research use only, not for human use.
Brief Description

D-Pantothenic acid, also called vitamin B5, is a water-soluble vitamin and an essential nutrient for many animals.
Description

D-Pantothenic acid, also called vitamin B5, is a water-soluble vitamin and an essential nutrient for many animals.
In Vitro

D-Pantothenic acid sodium is a precursor to coenzyme A and is primarily involved in energy production and lipid metabolism through the TCA cycle and the β-oxidation pathway, respectively.
In Vivo

Pantothenic acid (PTA; 3x10, 3x100, and 3x300 mg/kg) decreases Valproic acid (VPA; 300, 400, and 500 mg/kg, s.c.)-induced neural tube defects in mice. Animal Model:Female ICR mice weighing 29-35 gDosage:3x10, 3x100, and 3x300 mg/kg (10 mL/kg, volume administered) Administration:Injected intraperitoneally (i.p.) on day 8.5 of gestation Result:Significantly reduced VPA (300, 400, and 500 mg/kg, s.c.)-induced exencephaly, while none of the other external malformations such as open eyelid or skeletal malformations such as fused, absent, or bifurcated ribs and fused thoracic vertebrae and fused sternebrae were reduced.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

Other Indications
Indication

——

CAS Number

79-83-4
Formula Weight

219.24
Molecular Formula

C9H17NO5
Purity

>98% (HPLC)
Solubility

DMSO:44 mg/mL (200.69 mM); Ethanol:<1 mg/mL (<1 mM); Water:44 mg/mL (200.69 mM)
SMILES

CC(C)(CO)[C@H](C(=O)NCCC(=O)O)O
Chemical Name

——

1. Slyshenkov VS, et al. FEBS Lett,?004, 569(1-3), 169-172.

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